The research published in this report utilizes near-real-time data collected from social media platforms and remote sensing data sources to estimate seismic impacts in the 2023 M7.8 and M7.5 Turkey-Syria earthquake, including (1) infrastructure damage, (2) human mobility, and (3) human casualties. More specifically, we provide spatial estimates of building damage probability, communication network outages, evolving reports of casualties in Turkey and Syria, as well as how population density and human movement changed after the devastation. The information may help government and aid agencies as well as first responders better plan their rescuing and recovering activities, and provide research communities with high-quality data to better understand how disaster impacts evolve and how people respond in finer-grained temporal resolution.